Monday, 8 October 2012

Salex Topical


Generic Name: salicylic acid (Topical route)


sal-i-SIL-ik AS-id


Commonly used brand name(s)

In the U.S.


  • Akurza

  • Aliclen

  • Avosil

  • Betasal

  • Compound W

  • Corn Removing

  • Dermarest Psoriasis

  • DHS Sal

  • Drytex

  • Duofilm

  • Duoplant

  • Durasal

  • Freezone

  • Fung-O

  • Gets-It Corn/Callus Remover

  • Gordofilm

  • Hydrisalic

  • Ionil

  • Ionil Plus

  • Keralyt

  • Keralyt Scalp

  • Lupicare

  • Mediplast

  • Mg217 Sal-Acid

  • Mosco Corn & Callus Remover

  • Neutrogena

  • Occlusal-HP

  • Off-Ezy

  • Oxy Balance

  • P & S

  • Palmer's Skin Success Acne Cleanser

  • Propa pH

  • Salac

  • Sal-Acid Plaster

  • Salactic Film

  • Salex

  • Salitop

  • Salkera

  • Sal-Plant Gel

  • Salvax

  • Seba-Clear

  • Stri-Dex

  • Thera-Sal

  • Therasoft Anti-Acne

  • Tinamed

  • Ti-Seb

  • Virasal

  • Wart-Off Maximum Strength

  • Zapzyt

In Canada


  • Acnex

  • Acnomel Acne Mask

  • Clear Away Wart Removal System

  • Compound W One-Step Wart Remover

  • Compound W Plus

  • Dr. Scholl's Clear Away One Step Plantar Wart Remover

  • Dr. Scholl's Cushlin Ultra Slim Callus Removers

  • Dr. Scholl's Cushlin Ultra Slim Corn Removers

  • Duoforte 27

  • Freezone - One Step Callus Remover Pad

  • Freezone - One Step Corn Remover Pad

Available Dosage Forms:


  • Soap

  • Lotion

  • Liquid

  • Foam

  • Ointment

  • Gel/Jelly

  • Solution

  • Cream

  • Pad

  • Paste

  • Shampoo

  • Dressing

  • Stick

Therapeutic Class: Antiacne


Pharmacologic Class: NSAID


Chemical Class: Salicylate, Non-Aspirin


Uses For Salex


Salicylic acid is used to treat many skin disorders, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, common warts, and plantar warts, depending on the dosage form and strength of the preparation.


Some of these preparations are available only with your doctor's prescription.


Before Using Salex


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Young children may be at increased risk of unwanted effects because of increased absorption of salicylic acid through the skin. Also, young children may be more likely to get skin irritation from salicylic acid. Salicylic acid should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Salicylic acid should not be used in children younger than 2 years of age.


Geriatric


Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with this medicine.


Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Abciximab

  • Argatroban

  • Bivalirudin

  • Cilostazol

  • Citalopram

  • Clovoxamine

  • Dabigatran Etexilate

  • Dipyridamole

  • Escitalopram

  • Femoxetine

  • Flesinoxan

  • Fluoxetine

  • Fluvoxamine

  • Fondaparinux

  • Heparin

  • Lepirudin

  • Nefazodone

  • Paroxetine

  • Protein C

  • Rivaroxaban

  • Sertraline

  • Sibutramine

  • Ticlopidine

  • Tirofiban

  • Vilazodone

  • Zimeldine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acenocoumarol

  • Anisindione

  • Ardeparin

  • Azilsartan Medoxomil

  • Azosemide

  • Bemetizide

  • Bendroflumethiazide

  • Benzthiazide

  • Bumetanide

  • Buthiazide

  • Candesartan Cilexetil

  • Certoparin

  • Chlorothiazide

  • Chlorthalidone

  • Clopamide

  • Cyclopenthiazide

  • Dalteparin

  • Danaparoid

  • Dicumarol

  • Enoxaparin

  • Eprosartan

  • Ethacrynic Acid

  • Furosemide

  • Hydrochlorothiazide

  • Hydroflumethiazide

  • Indapamide

  • Irbesartan

  • Losartan

  • Methyclothiazide

  • Metolazone

  • Nadroparin

  • Olmesartan Medoxomil

  • Parnaparin

  • Phenindione

  • Phenprocoumon

  • Piretanide

  • Polythiazide

  • Probenecid

  • Reviparin

  • Tamarind

  • Tasosartan

  • Telmisartan

  • Tinzaparin

  • Torsemide

  • Trichlormethiazide

  • Valsartan

  • Warfarin

  • Xipamide

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Blood vessel disease

  • Diabetes mellitus (sugar diabetes)—Use of this medicine may cause severe redness or ulceration, especially on the hands or feet

  • Inflammation, irritation, or infection of the skin—Use of this medicine may cause severe irritation if applied to inflamed, irritated, or infected area of the skin

  • Influenza (flu) or

  • Varicella (chicken pox)—This medicine should not be used in children and teenagers with the flu or chicken pox. There is a risk of Reye's syndrome.

  • Kidney disease or

  • Liver disease—Using this medicine for a long time over large areas could result in unwanted effects

Proper Use of salicylic acid

This section provides information on the proper use of a number of products that contain salicylic acid. It may not be specific to Salex. Please read with care.


It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of absorption through the skin and the chance of salicylic acid poisoning.


If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap) to be applied over this medicine, make sure you know how to apply it. Since an occlusive dressing will increase the amount of medicine absorbed through your skin and the possibility of salicylic acid poisoning, use it only as directed. If you have any questions about this, check with your doctor.


Keep this medicine away from the eyes and other mucous membranes, such as the mouth and inside of the nose. If you should accidentally get some in your eyes or on other mucous membranes, immediately flush them with water for 15 minutes.


To use the cream, lotion, or ointment form of salicylic acid:


  • Apply enough medicine to cover the affected area, and rub in gently.

To use the gel form of salicylic acid:


  • Before using salicylic acid gel, apply wet packs to the affected areas for at least 5 minutes. If you have any questions about this, check with your health care professional.

  • Apply enough gel to cover the affected areas, and rub in gently.

To use the pad form of salicylic acid:


  • Wipe the pad over the affected areas.

  • Do not rinse off medicine after treatment.

To use the plaster form of salicylic acid for warts, corns, or calluses:


  • This medicine comes with patient instructions. Read them carefully before using.

  • Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.

  • Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.

  • Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.

  • Cut the plaster to fit the wart, corn, or callus and apply.

  • For corns and calluses:
    • Repeat every 48 hours as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.

    • Corns or calluses may be soaked in warm water for 5 minutes to help in their removal.


  • For warts:
    • Depending on the product, either:
      • Apply plaster and repeat every 48 hours as needed, or
        • Apply plaster at bedtime, leave in place for at least 8 hours, remove plaster in the morning, and repeat every 24 hours as needed.



    • Repeat for up to 12 weeks as needed, or as directed by your doctor, until wart is removed.


  • If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

To use the shampoo form of salicylic acid:


  • Before applying this medicine, wet the hair and scalp with lukewarm water. Apply enough medicine to work up a lather and rub well into the scalp for 2 or 3 minutes, then rinse. Apply the medicine again and rinse thoroughly.

To use the soap form of salicylic acid:


  • Work up a lather with the soap, using hot water, and scrub the entire affected area with a washcloth or facial sponge or mitt.

  • If you are to use this soap in a foot bath, work up rich suds in hot water and soak the feet for 10 to 15 minutes. Then pat dry without rinsing.

To use the topical solution form of salicylic acid for acne:


  • Wet a cotton ball or pad with the topical solution and wipe the affected areas.

  • Do not rinse off medicine after treatment.

To use the topical solution form of salicylic acid for warts, corns, or calluses:


  • This medicine comes with patient instructions. Read them carefully before using.

  • This medicine is flammable. Do not use it near heat or open flame or while smoking.

  • Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.

  • Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.

  • Avoid breathing in the vapors from the medicine.

  • Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.

  • Apply the medicine one drop at a time to completely cover each wart, corn, or callus. Let dry.

  • For warts—Repeat one or two times a day as needed for up to 12 weeks, or as directed by your doctor, until wart is removed.

  • For corns and calluses—Repeat one or two times a day as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.

  • Corns and calluses may be soaked in warm water for 5 minutes to help in their removal.

  • If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

Unless your hands are being treated, wash them immediately after applying this medicine to remove any medicine that may be on them.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For cream dosage form:
    • For corns and calluses:
      • Adults and children—Use the 2 to 10% cream as needed. Use the 25 to 60% cream one time every three to five days.



  • For gel dosage form:
    • For acne:
      • Adults and children—Use the 0.5 to 5% gel one time a day.


    • For psoriasis:
      • Adults and children—Use the 5% gel one time a day.


    • For common warts:
      • Adults and children—Use the 5 to 26% gel one time a day.



  • For lotion dosage form:
    • For acne:
      • Adults and children—Use the 1 to 2% lotion one to three times a day.


    • For dandruff and antiseborrhic dermatitis of the scalp:
      • Adults and children—Use the 1.8 to 2% lotion on the scalp one or two times a day.



  • For ointment dosage form:
    • For acne:
      • Adults and children—Use the 3 to 6% ointment as needed.


    • For psoriasis and seborrheic dermatitis:
      • Adults and children—Use the 3 to 10% ointment as needed.


    • For common warts:
      • Adults and children—Use the 3 to 10% ointment as needed. Use the 25 to 60% ointment one time every three to five days.



  • For pads dosage form:
    • For acne:
      • Adults and children—Use one to three times a day.



  • For plaster dosage form:
    • For corns, calluses, common warts, or plantar warts:
      • Adults and children—Use one time a day or one time every other day.



  • For shampoo dosage form:
    • For dandruff or seborrheic dermatitis of the scalp:
      • Adults and children—Use on the scalp one or two times a week.



  • For soap dosage form:
    • For acne:
      • Adults and children—Use as needed.



  • For topical solution dosage form:
    • For acne:
      • Adults and children—Use the 0.5 to 2% topical solution one to three times a day.


    • For common warts and plantar warts:
      • Adults and children—Use the 5 to 27% topical solution one or two times a day.


    • For corns and calluses:
      • Adults and children—Use the 12 to 27% topical solution one or two times a day.



Missed Dose


If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using Salex


When using salicylic acid, do not use any of the following preparations on the same affected area as this medicine, unless otherwise directed by your doctor:


  • Abrasive soaps or cleansers

  • Alcohol-containing preparations

  • Any other topical acne preparation or preparation containing a peeling agent (for example, benzoyl peroxide, resorcinol, sulfur, or tretinoin [vitamin A acid])

  • Cosmetics or soaps that dry the skin

  • Medicated cosmetics

  • Other topical medicine for the skin

To use any of the above preparations on the same affected area as salicylic acid may cause severe irritation of the skin.


Check with your doctor right away if you have nausea, vomiting, dizziness, loss of hearing, tinnitus, lethargy hyperpnea, diarrhea, and psychic disturbances. These could be symptoms of a serious condition called salicylate toxicity, especially in children under 12 years of age and patients with kidney or liver problems.


Salex Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor as soon as possible if any of the following side effects occur:


Less common or rare
  • Skin irritation not present before use of this medicine (moderate or severe)

Frequency not known
  • Dryness and peeling of skin

  • flushing

  • redness of skin

  • unusually warm skin

Symptoms of salicylic acid poisoning
  • Confusion

  • diarrhea

  • dizziness

  • fast or deep breathing

  • headache (severe or continuing)

  • hearing loss

  • lightheadedness

  • nausea

  • rapid breathing

  • ringing or buzzing in ears (continuing)

  • severe drowsiness

  • stomach pain

  • vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Skin irritation not present before use of this medicine (mild)

  • stinging

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Salex Topical side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Salex Topical resources


  • Salex Topical Side Effects (in more detail)
  • Salex Topical Use in Pregnancy & Breastfeeding
  • Salex Topical Drug Interactions
  • Salex Topical Support Group
  • 0 Reviews for Salex Topical - Add your own review/rating


Compare Salex Topical with other medications


  • Acne
  • Dermatological Disorders

Friday, 5 October 2012

Lysteda


Generic Name: tranexamic acid (Lysteda) (tran ex AM ik AS id)

Brand Names: Lysteda


What is tranexamic acid (Lysteda)?

Tranexamic acid is a man-made form of an amino acid (protein) called lysine. Tranexamic acid prevents enzymes in the body from breaking down blood clots.


Lysteda is used to treat heavy menstrual bleeding. This medication will not treat premenstrual syndrome (PMS).


Tranexamic acid may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Lysteda?


You should not use this medication if you are allergic to tranexamic acid, if you have problems with the blood vessels in your eyes, or if you have ever had a stroke, blood clot, or bleeding in your brain.

Before using this medicine, tell your doctor if you have kidney disease, leukemia, a history of endometriosis, or if your menstrual cycles are less than 21 days apart or longer than 35 days apart.


Do not start taking Lysteda until your period has started. Do not take it for longer than 5 days in a row. Talk with your doctor if your symptoms do not improve after 2 cycles of treatment.

Do not take more than 6 tablets in one 24-hour period.


Use a barrier form of birth control (such as a condom or diaphragm with spermicide). Hormonal contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may increase your risk of stroke, blood clot, or heart attack if they are used at the same time as Lysteda. Do not share Lysteda with another person, even if they have the same symptoms you have.

What should I discuss with my health care provider before taking Lysteda?


You should not take Lysteda if you are allergic to tranexamic acid, or if you have:

  • problems with the blood vessels in your eyes;




  • color blindness (only if you are receiving the injectable form of tranexamic acid);




  • a history of stroke;




  • if you have a history of bleeding in your brain; or




  • if you have recently had a blood clot.



To make sure you can safely take Lysteda, tell your doctor if you have any of these other conditions:



  • leukemia;



  • kidney disease;


  • a history of endometriosis; or




  • if your menstrual cycles are less than 21 days apart or longer than 35 days apart.




It is not known whether tranexamic acid will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Tranexamic acid can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone under 18 years old without your doctor's advice. Do not share Lysteda with another person, even if they have the same symptoms you have.

How should I use Lysteda?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


Do not start taking Lysteda until your period has started. Do not take it for longer than 5 days in a row.

Lysteda is usually taken three times per day for up to 5 days during your menstrual period. Do not take more than 6 tablets in one 24-hour period.


Take this medicine with a full glass of water.

You may take Lysteda with or without food.


Do not crush, chew, or break a Lysteda tablet. Swallow it whole.

Talk with your doctor if your symptoms do not improve after 2 cycles of treatment.


Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?


Take the missed dose as soon as you remember. Then take your next dose at least 6 hours later. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.


What should I avoid while taking Lysteda?


Avoid using a hormonal form of birth control such as birth control pills, injections, implants, skin patches, and vaginal rings. Hormonal contraception may increase your risk of stroke, blood clot, or heart attack while you are taking Lysteda. If you need to use birth control during treatment with Lysteda, use a barrier form (such as a condom or diaphragm with spermicide).

Lysteda side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Lysteda and call your doctor at once if you have a serious side effect such as:

  • problems with your vision (including color vision);




  • sudden numbness or weakness, especially on one side of the body;




  • sudden headache, confusion, problems with vision, speech, or balance;




  • sudden chest pain or trouble breathing;




  • pain or swelling in one or both legs;




  • migraine headache;




  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or




  • feeling like you might pass out.



Less serious side effects include:



  • mild headache;




  • runny or stuffy nose;




  • stomach pain;




  • tired feeling;




  • eye redness; or




  • back pain, joint or muscle pain.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Lysteda?


Tell your doctor about all other medicines you use, especially:



  • hormonal birth control (such as birth control pills, injections, implants, skin patches, and vaginal rings);




  • tretinoin (Vesanoid);




  • chemotherapy medication to treat leukemia;




  • any type of medication to treat a bleeding episode or a blood clot; or




  • factor IX (Bebulin VH, Konyne 80, Profilnine SD, Proplex T, and others).



This list is not complete and other drugs may interact with Lysteda. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Lysteda resources


  • Lysteda Side Effects (in more detail)
  • Lysteda Use in Pregnancy & Breastfeeding
  • Lysteda Drug Interactions
  • Lysteda Support Group
  • 13 Reviews for Lysteda - Add your own review/rating


  • Lysteda Advanced Consumer (Micromedex) - Includes Dosage Information

  • Lysteda Consumer Overview

  • Lysteda MedFacts Consumer Leaflet (Wolters Kluwer)

  • Lysteda Prescribing Information (FDA)

  • Tranexamic Acid Professional Patient Advice (Wolters Kluwer)

  • Cyklokapron Prescribing Information (FDA)

  • Cyklokapron Advanced Consumer (Micromedex) - Includes Dosage Information

  • Cyklokapron MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Lysteda with other medications


  • Menorrhagia
  • Menstrual Disorders


Where can I get more information?


  • Your doctor or pharmacist can provide more information about tranexamic acid (Lysteda).

See also: Lysteda side effects (in more detail)


Wednesday, 3 October 2012

Monistat 3


Generic Name: miconazole vaginal (my CAW nah zole)

Brand Names: M-Zole Dual Pack, Micon 7, Monistat 3, Monistat 5, Monistat 7


What is Monistat 3 (miconazole vaginal)?

Miconazole is an antifungal medication. It prevents fungus from growing.


Miconazole vaginal is used to treat vaginal candida (yeast) infections.


Miconazole vaginal may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about Monistat 3 (miconazole vaginal)?


Use this medication for the full amount of time prescribed by your doctor or recommended in the package even if you begin to feel better. The symptoms may improve before the infection is completely healed.


Avoid wearing tight-fitting, synthetic clothing (e.g., panty hose) that does not allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until the infection is healed.


Avoid getting this medication in the eyes, nose, or mouth.

What should I discuss with my healthcare provider before using Monistat 3 (miconazole vaginal)?


If this is the first time that you have ever had symptoms of a vaginal yeast infection, consult your doctor before using this medication.


Do not use miconazole vaginal if you have ever had an allergic reaction to it.

Before using miconazole vaginal, talk to your doctor if you have



  • a fever,




  • abdominal pain,




  • foul-smelling discharge,




  • diabetes, or




  • HIV or AIDS.



You may not be able to use miconazole vaginal, or you may require special monitoring during treatment if you have any of the conditions listed above.


Do not use miconazole vaginal without first talking to your doctor if you are pregnant. Do not use miconazole vaginal without first talking to your doctor if you are breast-feeding a baby.

How should I use Monistat 3 (miconazole vaginal)?


Use miconazole vaginal exactly as directed by your doctor or follow the directions that accompany the package. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Wash your hands before and after using the medication.


Insert the tablet, suppository, or cream into the vagina using the applicator as directed.


Use this medication for the full amount of time prescribed by your doctor or recommended in the package even if you begin to feel better. The symptoms may improve before the infection is completely healed.


Use this medication continuously, even during your menstrual period.


You can use a sanitary napkin to prevent the medication from staining your clothing but do not use a tampon.


If the infection does not clear up after you have finished one course of therapy, or if it appears to get worse, see your doctor. You may have another type of infection.


Avoid getting this medication in the eyes, nose, or mouth. Store miconazole vaginal at room temperature away from moisture and heat.

What happens if I miss a dose?


Apply the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and apply only the next regularly scheduled dose. Do not use a double dose of this medication.


What happens if I overdose?


An overdose of miconazole vaginal is unlikely. If you do suspect that a much larger than normal dose has been used or that miconazole vaginal has been ingested, contact an emergency room or a poison control center.


What should I avoid while using Monistat 3 (miconazole vaginal)?


Avoid wearing tight-fitting, synthetic clothing (e.g., panty hose) that does not allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until the infection is healed.


Miconazole may damage a condom or diaphragm. Use another form of birth control while using miconazole vaginal.


Monistat 3 (miconazole vaginal) side effects


Stop using miconazole vaginal and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of your throat; swelling of your lips, face, or tongue; or hives).

Other, less serious side effects may be more likely to occur. These include burning, itching, irritation of the skin, and an increased need to urinate.


Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Monistat 3 (miconazole vaginal)?


Do not use miconazole vaginal without first talking to your doctor if you are taking warfarin (Coumadin). Special monitoring or a dosage adjustment may be necessary.

Avoid using other vaginal creams or douches at the same time as miconazole vaginal unless otherwise directed by your doctor.


Drugs other than those listed here may also interact with miconazole vaginal. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.



More Monistat 3 resources


  • Monistat 3 Side Effects (in more detail)
  • Monistat 3 Use in Pregnancy & Breastfeeding
  • Monistat 3 Drug Interactions
  • Monistat 3 Support Group
  • 0 Reviews for Monistat 3 - Add your own review/rating


  • Monistat 3 Prescribing Information (FDA)

  • Monistat 3 Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Baza Antifungal Topical Advanced Consumer (Micromedex) - Includes Dosage Information

  • Cruex Prescription Strength Topical Advanced Consumer (Micromedex) - Includes Dosage Information

  • Lotrimin AF Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Micatin Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Monistat 7 Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Zeasorb-AF Gel MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Monistat 3 with other medications


  • Vaginal Yeast Infection


Where can I get more information?


  • Your pharmacist has additional information about miconazole vaginal written for health professionals that you may read.

See also: Monistat 3 side effects (in more detail)


Monday, 1 October 2012

Lopressor



Generic Name: metoprolol (Oral route)

met-oh-PROE-lol

Oral route(Tablet, Extended Release)

Following abrupt cessation of therapy with certain beta-blocking agents, exacerbations of angina pectoris and, in some cases, myocardial infarction have occurred. The dosage should be gradually reduced over a period of 1 to 2 weeks and the patient should be carefully monitored when discontinuing chronic therapy. If angina markedly worsens or acute coronary insufficiency develops, metoprolol succinate administration should be reinstated promptly, at least temporarily, and other measures appropriate for the management of unstable angina should be taken. Patients should be warned against interruption or discontinuation of therapy without the physician's advice .


Oral route(Tablet)

Following abrupt cessation of therapy with certain beta-blocking agents, exacerbations of angina pectoris and, in some cases, myocardial infarction have occurred. The dosage should be gradually reduced over a period of 1 to 2 weeks and the patient should be carefully monitored when discontinuing chronic therapy. If angina markedly worsens or acute coronary insufficiency develops, metoprolol tartrate administration should be reinstated promptly, at least temporarily, and other measures appropriate for the management of unstable angina should be taken. Patients should be warned against interruption or discontinuation of therapy without the physician's advice. Because coronary artery disease is common and may be unrecognized, it may be prudent not to discontinue metoprolol tartrate therapy abruptly even in patients treated only for hypertension .



Commonly used brand name(s)

In the U.S.


  • Lopressor

  • Toprol XL

Available Dosage Forms:


  • Tablet, Extended Release

  • Tablet

Therapeutic Class: Cardiovascular Agent


Pharmacologic Class: Beta-Adrenergic Blocker, Cardioselective


Uses For Lopressor


Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk for heart attacks. These problems may be less likely to occur if blood pressure is controlled.


Metoprolol is also used to treat severe chest pain (angina) and lowers the risk of repeated heart attacks. It is given to people who have already had a heart attack. In addition, metoprolol is used to treat patients with heart failure.


This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.


This medicine is available only with your doctor's prescription.


Before Using Lopressor


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of metoprolol tablets in the pediatric population. Safety and efficacy have not been established.


Appropriate studies have not been performed on the relationship of age to the effects of metoprolol extended-release tablets in children younger than 6 years of age. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of metoprolol in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require an adjustment in the dose for patients receiving metoprolol.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Albuterol

  • Amiodarone

  • Arformoterol

  • Bambuterol

  • Bitolterol

  • Broxaterol

  • Clenbuterol

  • Clonidine

  • Colterol

  • Diltiazem

  • Dronedarone

  • Fenoldopam

  • Fenoterol

  • Formoterol

  • Hexoprenaline

  • Indacaterol

  • Isoetharine

  • Levalbuterol

  • Lidocaine

  • Metaproterenol

  • Pirbuterol

  • Procaterol

  • Reproterol

  • Rimiterol

  • Ritodrine

  • Salmeterol

  • Terbutaline

  • Tretoquinol

  • Tulobuterol

  • Verapamil

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acarbose

  • Aceclofenac

  • Acemetacin

  • Acetohexamide

  • Alclofenac

  • Alfuzosin

  • Amlodipine

  • Apazone

  • Arbutamine

  • Benfluorex

  • Benoxaprofen

  • Bromfenac

  • Bufexamac

  • Bunazosin

  • Bupropion

  • Carprofen

  • Chlorpropamide

  • Cimetidine

  • Citalopram

  • Clometacin

  • Clonixin

  • Dexketoprofen

  • Diclofenac

  • Diflunisal

  • Digoxin

  • Diphenhydramine

  • Dipyrone

  • Doxazosin

  • Droxicam

  • Escitalopram

  • Etodolac

  • Etofenamate

  • Felbinac

  • Felodipine

  • Fenbufen

  • Fenoprofen

  • Fentiazac

  • Floctafenine

  • Flufenamic Acid

  • Fluoxetine

  • Flurbiprofen

  • Gliclazide

  • Glimepiride

  • Glipizide

  • Gliquidone

  • Glyburide

  • Guar Gum

  • Hydralazine

  • Hydroxychloroquine

  • Ibuprofen

  • Indomethacin

  • Indoprofen

  • Insulin

  • Insulin Aspart, Recombinant

  • Insulin Glulisine

  • Insulin Lispro, Recombinant

  • Isoxicam

  • Ketoprofen

  • Ketorolac

  • Lacidipine

  • Lercanidipine

  • Lornoxicam

  • Manidipine

  • Meclofenamate

  • Mefenamic Acid

  • Meloxicam

  • Metformin

  • Mibefradil

  • Miglitol

  • Moxisylyte

  • Nabumetone

  • Naproxen

  • Nicardipine

  • Nifedipine

  • Niflumic Acid

  • Nilvadipine

  • Nimesulide

  • Nimodipine

  • Nisoldipine

  • Nitrendipine

  • Oxaprozin

  • Oxyphenbutazone

  • Paroxetine

  • Phenelzine

  • Phenobarbital

  • Phenoxybenzamine

  • Phentolamine

  • Phenylbutazone

  • Pirazolac

  • Piroxicam

  • Pirprofen

  • Pranidipine

  • Prazosin

  • Propafenone

  • Propoxyphene

  • Propyphenazone

  • Proquazone

  • Quinidine

  • Repaglinide

  • Rifampin

  • Rifapentine

  • Ritonavir

  • St John's Wort

  • Sulindac

  • Suprofen

  • Tamsulosin

  • Telithromycin

  • Tenidap

  • Tenoxicam

  • Terazosin

  • Terbinafine

  • Thioridazine

  • Tiaprofenic Acid

  • Tolazamide

  • Tolbutamide

  • Tolmetin

  • Trimazosin

  • Troglitazone

  • Urapidil

  • Venlafaxine

  • Zomepirac

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Angina (chest pain) or

  • Hypotension (low blood pressure) or

  • Peripheral vascular disease (clogged blood vessels) or

  • Pheochromocytoma (adrenal gland tumor)—Use with caution. May make these conditions worse.

  • Blood circulation problems, severe or

  • Bradycardia, severe (slow heartbeat) or

  • Heart block (heart rhythm problem) or

  • Heart failure, acute and severe or

  • Lung disease (e.g., asthma, bronchitis, emphysema) or

  • Sick-sinus syndrome (heart rhythm problem)—Should not be used in patients with these conditions.

  • Diabetes or

  • Hyperthyroidism (overactive thyroid) or

  • Hypoglycemia (low blood sugar)—May cover up some of the symptoms of these diseases, such as a fast heartbeat.

  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of metoprolol

This section provides information on the proper use of a number of products that contain metoprolol. It may not be specific to Lopressor. Please read with care.


Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you.


In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.


Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.


Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, strokes, or kidney disease.


Do not interrupt or stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. Some conditions may become worse when the medicine is stopped suddenly, which can be dangerous.


Take this medicine with a meal or just after you eat. You may break the extended-release tablet into two pieces, but swallow the two pieces whole and do not crush or chew them.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For acute heart attack or heart failure:
    • For oral dosage form (extended-release tablets):
      • Adults—At first, 25 milligrams (mg) once a day for 2 weeks. In patients with severe heart failure, the starting dose is 12.5 mg once a day. Your doctor may adjust your dose as needed.

      • Children—Use and dose must be determined by your doctor.


    • For oral dosage form (tablets):
      • Adults—At first, 50 milligrams (mg) every 6 hours for 2 days. Then, 100 mg two times a day. The medicine will be started in the hospital.

      • Children—Use and dose must be determined by your doctor.



  • For chest pain:
    • For oral dosage form (extended-release tablets):
      • Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 400 mg per day.

      • Children—Use and dose must be determined by your doctor.


    • For oral dosage form (tablets):
      • Adults—At first, 100 milligrams (mg) per day, given in two divided doses. Your doctor may adjust your dose if needed. However, the dose is usually not more than 400 mg per day.

      • Children—Use and dose must be determined by your doctor.



  • For high blood pressure:
    • For oral dosage form (extended-release tablets):
      • Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 400 mg per day.

      • Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight per day, given as a single dose. The first dose should not be more than 50 mg per day.

      • Children younger than 6 years of age—Use and dose must be determined by your doctor.


    • For oral dosage form (tablets):
      • Adults—At first, 100 milligrams (mg) per day, given as a single dose or in divided doses. Your doctor may adjust your dose if needed. However, the dose is usually not more than 450 mg per day.

      • Children—Use and dose must be determined by your doctor. .



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Lopressor


It is very important that your doctor check the progress of you or your child at regular visits to make sure this medicine is working properly and to check for unwanted effects.


Metoprolol may worsen the symptoms of heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; weight gain; or wheezing.


This medicine may cause changes in blood sugar levels. Also, this medicine may cover up the symptoms of low blood sugar, such as a rapid pulse rate. Check with your doctor if you or your child notice a change in your normal symptoms or a change in the results of your blood or urine sugar tests.


Make sure any doctor or dentist who treats you or your child knows that you are using this medicine. You may need to stop using this medicine several days before having surgery.


This medicine may cause some people to become less alert than they are normally. If this side effect occurs, do not drive, use machines, or do anything else that could be dangerous if you are not alert.


Dizziness, lightheadedness, or even fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


Lopressor Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Blurred vision

  • chest pain or discomfort

  • confusion

  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

  • shortness of breath

  • slow or irregular heartbeat

  • sweating

  • unusual tiredness or weakness

Less common
  • Bloating or swelling of the face, arms, hands, lower legs, or feet

  • cough

  • decreased urine output

  • difficult or labored breathing

  • difficulty with speaking

  • dilated neck veins

  • disturbed color perception

  • double vision

  • extreme fatigue

  • fast, pounding, or racing heartbeat or pulse

  • halos around lights

  • headache

  • inability to move the arms, legs, or facial muscles

  • inability to speak

  • irregular breathing

  • loss of vision

  • night blindness

  • noisy breathing

  • overbright appearance of lights

  • pain, tension, and weakness upon walking that subsides during periods of rest

  • paleness or cold feeling in the fingertips and toes

  • rapid weight gain

  • seeing, hearing, or feeling things that are not there

  • short-term memory loss

  • slow speech

  • swelling of the face, fingers, feet, or lower legs

  • tightness in the chest

  • tingling of the hands or feet

  • tingling or pain in the fingers or toes when exposed to cold

  • troubled breathing

  • tunnel vision

  • unusual weight gain or loss

  • wheezing

Rare
  • Bluish color skin of the fingers or toes

  • chills

  • clay-colored stools

  • continuing loss of appetite

  • continuing or severe abdominal or stomach pain

  • continuing or severe nausea and vomiting

  • dark urine

  • difficulty with moving

  • fever

  • general tiredness and weakness

  • hoarseness

  • increased frequency of urination

  • itching skin

  • light-colored stools

  • lower back or side pain

  • muscle pain or stiffness

  • numbness of the fingers or toes

  • pain, swelling, or redness in the joints

  • painful or difficult urination

  • rash

  • sore throat

  • sores, ulcers, or white spots on the lips or in the mouth

  • unpleasant breath odor

  • unusual bleeding or bruising

  • upper right abdominal or stomach pain

  • vomiting of blood

  • weakness

  • yellow eyes and skin

Incidence not known
  • Black, tarry stools

  • bleeding gums

  • blood in the urine or stools

  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • cool, sweaty skin

  • pinpoint red spots on the skin

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of overdose
  • Bluish color of the fingernails, lips, skin, palms, or nail beds

  • change in consciousness

  • loss of consciousness

  • no blood pressure or pulse

  • stopping of heart

  • unconsciousness

  • very drowsy or sleepy

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • Belching

  • bloated

  • decreased interest in sexual intercourse

  • difficulty having a bowel movement (stool)

  • discouragement

  • dry mouth

  • excess air or gas in stomach or intestines

  • feeling of constant movement of self or surroundings

  • feeling of indigestion

  • feeling sad or empty

  • full feeling

  • inability to have or keep an erection

  • irritability

  • loss in sexual ability, desire, drive, or performance

  • loss of interest or pleasure

  • nightmares

  • pain in the chest below the breastbone

  • passing gas

  • redness or other discoloration of the skin

  • runny nose

  • sensation of spinning

  • sleeplessness

  • sneezing

  • stuffy nose

  • tiredness

  • trouble concentrating

  • trouble sleeping

  • unable to sleep

Rare
  • Bone pain

  • continuing ringing or buzzing or other unexplained noise in the ears

  • dry eyes

  • hair loss or thinning of the hair

  • hearing loss

  • increased sensitivity of the skin to sunlight

  • pain of penis on erection

  • severe sunburn

Incidence not known
  • Change in taste or bad, unusual, or unpleasant (after) taste

  • fear or nervousness

  • hives or welts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Lopressor side effects (in more detail)



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More Lopressor resources


  • Lopressor Side Effects (in more detail)
  • Lopressor Use in Pregnancy & Breastfeeding
  • Drug Images
  • Lopressor Drug Interactions
  • Lopressor Support Group
  • 8 Reviews for Lopressor - Add your own review/rating


  • Lopressor Concise Consumer Information (Cerner Multum)

  • Lopressor Prescribing Information (FDA)

  • Lopressor MedFacts Consumer Leaflet (Wolters Kluwer)

  • Metoprolol Prescribing Information (FDA)

  • Metoprolol Professional Patient Advice (Wolters Kluwer)

  • Metoprolol Succinate Monograph (AHFS DI)

  • Toprol-XL Prescribing Information (FDA)



Compare Lopressor with other medications


  • Angina
  • Angina Pectoris Prophylaxis
  • Atrial Fibrillation
  • Benign Essential Tremor
  • Heart Attack
  • High Blood Pressure
  • Left Ventricular Dysfunction
  • Mitral Valve Prolapse
  • Premature Ventricular Depolarizations
  • Supraventricular Tachycardia